Enhanced fitness relates to reduced cerebrovascular reactivity and perfusion in a sample of very healthy older adults
Aims : To understand relationship between fitness and grey matter volume(GMV), cerebral blood flow(CBF) and cerebrovascular reactivityC(VR)
Anatomical, CBF and CVR information are collected by MRI acquisitions in all participants.
Results revealed decreased CVR was associated with increased fitness throughout large areas of the cerebral cortex.
Lower fitness was associated with higher CBF and a slower hemodynamic response.
Authors : Brittany Intzandt, Dalia Sabra, Catherine Foster, Laurence Desjardins-Crépeau, Rick Hoge, Christopher J Steele, Louis Bherer, Claudine J Gauthier.
Clinical Application : Vascular aging / Fitness
Country : Canada
Date Publication : 2018